|Image from The Truth About Cancer|
What is ketosis as a metabolic treatment of cancer? Ketosis was a beneficial process the human body developed as an adaptation to times when food was unavailable. Cancer cells rely on glucose for energy and they cannot function without it. By its nature, the ketogenic diet is very low in carbohydrates (typically 20 to 50 grams/day). This provides minimal energy to cancer cells. Cancer cells cannot use the ketones produced when the body breaks down fat for energy.
30-50g / day carb.s
>70g / day protein
Starve Cancer glucose feeds cancer (food pyramid)
- 3-day water fast
- Intermittent fasting to hold ketosis
- Blood glucose = 70 mg/dl
- Blood ketones = minimum 3.6
- MCT oil - allows more carb intake while remaining in ketosis
- Berberine - assists glucose metabolism
- ALA - facilitates ketosis and enhances insulin sensitivity
- Fenugreek - enhances insulin sensitivity and helps control blood glucose
AVOID ALL CARB.S & SUGAR!!!
Take away cancer's fuel source! Stay away from ALL sugar, agave, gluten, grains, root vegetables, and most fruit, wheat, oats, rice, quinoa, bread, pasta, beans, legumes, milk and reduced fat dairy, processed meat
Avoid these Oils
cotton seed, sunflower, safflower, soy, canola
Avoid ALL Alcohol
(I avoid ALL artificial sweeteners including "diet" drinks)
2. Sucralose - Splenda is a toxin
5. Glucose - dextrose
6. Galactose - milk
7. Fructose - fruit
8. Honey - 50% fructose
According to the ketogenic diet, it's okay to use liquid 100% organic stevia and xylitol though I choose not to.
Ketogenic Fats - 60-70% caloric intake
Fats and Oil
MCT oil / powder
Nuts and Seeds (in moderation)
Full fat dairy and cheeses
Cottage cheese - full fat
High quality meat
NO cured meats
Get your carb.s from leafy green vegetables that grow above ground NO ROOT VEGETABLES
Mung bean sprouts
Hearts of Palm
Fruit: (fructose is as bad or worse than glucose - avoid most fruits)
Unsweetened almond milk
Organic Acids and Enzymes:
Unsweetened fermented drinks
Dried herbs without added sugar
Apple cider vinegar
Some companies add sugar and other things to spice-mixes
Otto Heinrich Warburg
German physiologist/biochemist: - 1931 - won Nobel Prize for his discovery: Cancer as a Metabolic Disease
Wasteful Metabolism: cancer cells prefer anaerobic process of fermentation = conversion of sugar into acids, gases, and alcohol.
Fast growing cancer cells take the "cheaper" easier path of fermentation.
- Cells became cancerous by damaged cellular respiration. Mitochondria burn oxygen and glucose = ATP.
- Cells deprived of oxygen revert to energy production known as fermentation (anaerobic - no oxygen needed).
3. Fermentation of glucose produces lactic acid causes cancer cells to be very hungry.
Somatic Mutation Theory - Cancer as a genetic disease became mainstream and the Metabolic Theory faded out in 1970 until it's revival via Prof. Thomas Seyfried.
Geneticist Prof. Thomas Seyfried:
Cancer as a Metabolic Disease examined mitochondrial DNA = no mutations found.
Cancer cells ferment glucose and glutamine to produce energy = food for cancer
All Cancer: defect in Cardiolipin = lipid fat which, composes the membrane of mitochondria that directly controls oxidative phosphorylation
Conclusion: cellular DNA becomes cancerous due to need of cells to ferment.
*Oncogenes drive fermentation
*Damaged respiration = free radicals + lactic acid which create mutations
Therapies: TAKE AWAY CANCER'S FUEL SOURCE = GLUCOSE
CR: Caloric restriction effect.
Lower blood glucose - raise ketones = kill cancer cells
Biomarkers for CR Caloric Restriction:
- LOWER blood glucose
- Elevate blood ketone bodies
Ketosis drives blood sugar way down
Autophagy - cells "house cleaning" breaks down and recycles defective mitochondria. Autophagy is triggered by nutritional ketosis.
Anti Tumor Effects of CR: calorie restriction
- Pro-apoptotic = death of cancer cells
Anti-glycotic drugs: reduce glycolysis (fermentation)
CR - drugs lower glucose levels
KD-R with glycolysis inhibitor 2-DG for managing CT - 2A astrocytoma
All information provided here is a culmination of my personal research, reading, listening, and watching videos and podcasts. I am NOT a nutritionist nor a medical doctor. I do not provide medical services or treatment plans. This post is intended as an update of my own interest in the Ketogenic Lifestyle. Always consult with your medical team about your treatment.